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While the price goes up, so does the fun when you opt to enjoy your time with any one of these Los Angeles female escorts. The LCT gene is a locus well-documented as showing substantial genetic differentiation within Europe [29] , [30]. September 25, Published. In a large GWAS based on subjective categorization of hair color [9] , the strongest genetic effect detected was also at rs Journal of human evolution This observation, combined with the clustering of individuals in the PCA by country and the genetic homogeneity within each country revealed by the PLINK neighbor analysis, motivated our choice to correct the population structure in the GWAS and the replication study by using the country of sampling instead of the genetic PCs as covariates.

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These countries, located near the geographical extremes of Europe, were chosen to capture a large fraction of European phenotypic variation. For eye pigmentation, the iris color score C was calculated from the analysis of digital photographs taken under controlled light conditions using a cardboard box with form fitting foam padding such that the only illumination was from the camera flash. Studies including larger sample sizes are needed to characterize the RQ variant effect on skin pigmentation. View Article Google Scholar 3. The LCT gene is a locus well-documented as showing substantial genetic differentiation within Europe [29] , [30].

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Description: The percent variance explained is greatest in Poland, where there is the largest variation in eye color. Individuals from Ireland, Poland, Italy, and Portugal are colored in yellow, red, blue, and gray, respectively. Given the conspicuousness of hair, eye, and skin color, a reasonable hypothesis is that variation in these traits has been shaped by sexual selection [6] , 7. A GWAS was conducted for the three quantitative pigmentation phenotypes in women across , SNP loci, and replication of the most significant associations was attempted in a sample of European men and women from the same countries. View Article Google Scholar Wellcome Trust Case Control Consortium Genome-wide association study of 14, cases of seven common diseases and 3, shared controls. We find that the pigmentation phenotypes are highly stratified along axes of European genetic differentiation.
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